Chemoprophylaxis of Shigella flexneri Keratoconjunctivitis in Rabbits
AUTOR(ES)
Cross, W. R.
RESUMO
Chloramphenicol, chlortetracycline, streptomycin, and sulfisoxazole prevented keratoconjunctivitis in rabbit eyes infected with Shigella flexneri. The route of administration of the agent and the dose were important variables in controlling the infectious process. This assay system appears to be a useful technique for the in vivo evaluation of chemotherapeutic agents.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=376967Documentos Relacionados
- A Chromosomal Locus Which Controls the Ability of Shigella flexneri to Evoke Keratoconjunctivitis
- Lactoferrin Protects Rabbits from Shigella flexneri-Induced Inflammatory Enteritis
- Susceptibility of Rabbits Immunized with Mycobacterium bovis (BCG) or Mycobacterium phlei to Shigella Keratoconjunctivitis
- Rough mutant of Shigella flexneri 2a that penetrates tissue culture cells but does not evoke keratoconjunctivitis in guinea pigs.
- HeLa cell invasiveness and O antigen of Shigella flexneri as separate and prerequisite attributes of virulence to evoke keratoconjunctivitis in guinea pigs.
