Choroidal malignant melanoma in an albino.
AUTOR(ES)
Casswell, A G
RESUMO
This is the first report of an amelanotic melanoma arising in the unpigmented choroid of a tyrosinase-positive oculocutaneous albino (TPOCA). Melanosomes within the tumour showed a maturation arrest in the unpigmented type II (premelanosome) phase. Other neural crest derived melanocytes in iris and choroid showed similar limited melanogenesis. The neuroectodermally derived melanocytes of the iris, ciliary body, and retinal pigment epithelium (RPE) contained mature melanosomes, though clinically the RPE was pale. The significance of this tumour arising in an albinotic eye is discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1041897Documentos Relacionados
- Choroidal malignant melanoma in a child.
- Pattern of mortality in choroidal malignant melanoma.
- Local recurrence of choroidal malignant melanoma following enucleation.
- Choroidal malignant melanoma in association with oculodermal melanocytosis in a black patient.
- Complete infarction of the eye complicating a choroidal malignant melanoma.