Chromosomal location of the gene encoding phosphoribosylpyrophosphate synthetase in Escherichia coli.
AUTOR(ES)
Hove-Jensen, B
RESUMO
A mutant of Escherichia coli with a partially defective phosphoribosylpyrophosphate synthetase (ribosephosphate pyrophosphokinase) has been characterized genetically. The genetic lesion causing the altered phosphoribosylpyrophosphate synthetase, prs, was mapped at 26 min on the linkage map by conjugation. Transductional analysis of the prs region established the gene order as purB-fadR-dadR-tre-pth-prs-hemA-trp. Two additional mutations were identified in the mutant: one in gsk, the gene encoding guanosine kinase, and one in lon, conferring a mucoid colony morphology. The contribution of each mutation to the phenotype of the mutant has been evaluated.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=217445Documentos Relacionados
- Transcription of the folC gene encoding folylpolyglutamate synthetase-dihydrofolate synthetase in Escherichia coli.
- Physical map location of the Escherichia coli gene encoding acyl coenzyme A synthetase.
- Chromosomal location and structure of the operon encoding peptide-chain-release factor 2 of Escherichia coli.
- Chromosomal location of a structural gene for the RNA polymerase sigma factor in Escherichia coli.
- Structure of the gene encoding phosphoribosylpyrophosphate synthetase (prsA) in Salmonella typhimurium.
