Chronic arthritis associated with the presence of intrasynovial rubella virus.
AUTOR(ES)
Grahame, R
RESUMO
In this report we present 21 instances in which live rubella virus was isolated from synovial fluid obtained from 6 cases of inflammatory oligoarthritis or polyarthritis over a period of 2 years in the absence of firm clinical evidence of rubella. In 3 cases (cases 1, 2, 6,) a persistent oligoarthritis predominantly affecting the knee joints occurred in 2 adult women and one man, lasting to date 27, 29, and 18 months respectively, and in one of these cases virions were found in cells of the synovial membrane. In case 3 a boy of 9 presented with an illness indistinguishable from the systemic variety of juvenile chronic arthritis (Still's disease). In case 4 a young man with persistent monoarthritis was found to have ankylosing spondylitis, and in case 5 a progressive erosive polyarthritis developed 5 years after an attack of rubella complicated by rubella arthritis. The virus was identified by a variety of virological techniques and infection confirmed by immunofluorescence and (in one case) electron microscopy.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1001051Documentos Relacionados
- Chronic arthritis associated with the presence of intrasynovial rubella virus
- Cellular hyperimmunoreactivity to rubella virus synthetic peptides in chronic rubella associated arthritis.
- Rubella-Associated Arthritis: Rescue of Rubella Virus from Peripheral Blood Lymphocytes Two Years Postvaccination
- Bell's palsy and infection with rubella virus.
- Rubella-associated arthritis. I. Comparative study of joint manifestations associated with natural rubella infection and RA 27/3 rubella immunisation.
