Coagulase expression in Staphylococcus aureus is positively and negatively modulated by an agr-dependent mechanism.

AUTOR(ES)

Lebeau, C

RESUMO

Expression of staphylocoagulase by agr+ Staphylococcus aureus depends on the growth phase, being maximal during exponential growth and decreasing sharply postexponentially, while an agr-deleted strain continuously expresses an intermediate level of coagulase. Therefore, coagulase expression appears to be both positively and negatively modulated by an agr-dependent mechanism.

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