Comparative evaluation of two test methods (enzyme immunoassay and latex fixation) for the detection of heterophil antibodies in infectious mononucleosis.
AUTOR(ES)
Kim, M
RESUMO
The present study evaluated the Ventrescreen Mono enzyme immunoassay (Ventrex Laboratories) and Monolatex (Wampole Laboratories) for detection of infectious mononucleosis-specific heterophil antibodies by comparing test results on sera of 247 symptomatic patients. The purpose of this study was to compare not only the two different test systems but also the two different methods they represent for accuracy in detecting infectious mononucleosis-specific heterophil antibodies. Discrepancies in the test results of the two kits were arbitrated by determining the Epstein-Barr virus antibody profiles of the samples. The study showed that the Ventrescreen Mono enzyme immunoassay is as good as the Monolatex test for detecting heterophil antibodies. After discrepancies were resolved, the sensitivity and specificity of the Ventrescreen assay were 100 and 98%, respectively.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=268216Documentos Relacionados
- Latex test for serodiagnosis of infectious mononucleosis.
- Comparative evaluation of three commercial tests for detection of heterophile antibody in patients with infectious mononucleosis.
- Evaluation of latex-based heterophile antibody assay for diagnosis of acute infectious mononucleosis.
- Measurement of heterophil antibody and antibodies to EB viral capsid antigen IgG and IgM in suspected cases of infectious mononucleosis.
- Detection of infectious mononucleosis heterophil antibody by a rapid, standardized enzyme-linked immunosorbent assay procedure.
