Comparative studies of a new commercial kit for the estimation of vitamin B12 in serum.
AUTOR(ES)
Waters, H M
RESUMO
A commercial kit method (Technia Diagnostics) for the estimation of serum vitamin B12 claiming certain practical advantages was examined. Analytical and clinical performance were compared with a non-commercial radioisotope B12 method, previously compared to other commercial radioisotope B12 methods. The kit's analytical performance in our hands was satisfactory, although the within-batch precision and recovery of added cyanocobalamin were disappointing. Clinical performance was comparable with the non-commercial B12 method. Establishment of suitable reference ranges as a prerequisite to diagnostic use is apparent.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=494208Documentos Relacionados
- Experience with a commercial kit for the radioisotopic assay of vitamin B12 in serum: the Phadebas B12 Test
- Vitamin B12 absorption studies: effect of parenteral non-radioactive vitamin B12 on serum level of 57Co vitamin B12
- Limitations of protein-coated charcoal in the separation of free from bound vitamin B12 in serum.
- The Role of the Pancreas in Vitamin B12 Absorption: Studies of Vitamin B12 Absorption in Partially Pancreatectomized Rats
- Comparative studies on the microbiological vitamin B12 assay at two laboratories.
