'Compensatory slippage' in the evolution of ribosomal RNA genes.
AUTOR(ES)
Hancock, J M
RESUMO
The distribution patterns of shared short repetitive motifs in the expansion segments of the large subunit rRNA genes of different species show that these segments are coevolving as a set and that in two examined vertebrate species the RNA secondary structures are conserved as a consequence of runs of motifs in one region being compensated by complementary motifs in another. These unusual processes, involving replication-slippage, have implications for the evolution of ribosomal RNA and for the use of the rDNA multigene family as a 'molecular clock' for assessing relationships between species.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=332389Documentos Relacionados
- Conserved features in the mode of replication of eukaryotic ribosomal RNA genes.
- 5-Methyldeoxycytidine in the Physarum minichromosome containing the ribosomal RNA genes.
- Transcription termination and RNA processing in the 3'-end spacer of mouse ribosomal RNA genes.
- Replication and meiotic transmission of yeast ribosomal RNA genes.
- Variation among human 28S ribosomal RNA genes.