COMPLEX MITOCHONDRIAL DNA IN LEUKEMIC AND NORMAL HUMAN MYELOID CELLS*
AUTOR(ES)
Clayton, David A.
RESUMO
Mitochondrial DNA's from the peripheral blood of 14 patients with granulocytic leukemia contained a circular dimer form. No such structure could be found in M DNA's from three patients with nonmalignant proliferations of granulocytes. The frequency of the circular dimer form is reduced upon treatment with antileukemic drugs. The above results suggest that a significant relation exists between the formation and presence of the circular dimer M DNA form and granulocytic leukemia in man.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=223617Documentos Relacionados
- Uptake of Transfer Ribonucleic Acid by Normal and Leukemic Cells*
- Nuclear DNA Sequences Present in Human Leukemic Cells and Absent in Normal Leukocytes
- Nuclear DNA sequences present in human leukemic cells and absent in normal leukocytes
- Telomeric DNA in normal and leukemic blood cells.
- Gamma-interferon induces expression of the HLA-D antigens on normal and leukemic human myeloid cells.
