Comprehensive de novo structure prediction in a systems-biology context for the archaea Halobacterium sp. NRC-1

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BioMed Central

RESUMO

Simultaneous analysis of the association network, coordinated mRNA level changes in microarray experiments and genome-wide structure prediction of the three-dimensional structure of 1,185 proteins and protein domains provided insights into the roles of several Halobacterium NRC-1 proteins of previously unknown function.

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