Construction of Urease-Negative Mutants of Yersinia enterocolitica Serotypes O:3 and O:8: Role of Urease in Virulence and Arthritogenicity
AUTOR(ES)
Gripenberg-Lerche, Christel
FONTE
American Society for Microbiology
RESUMO
Yersinia enterocolitica serotype O:3 and O:8 urease-negative mutants unable to express the 19-kDa β subunit of urease were constructed and tested for virulence and arthritogenicity. Our results indicate that urease is needed for full virulence in oral infections and that it is not an arthritogenic factor in the rat model.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=97227Documentos Relacionados
- Construction of isogenic urease-negative mutants of Helicobacter pylori by allelic exchange.
- Role of YadA in arthritogenicity of Yersinia enterocolitica serotype O:8: experimental studies with rats.
- Role of YadA-mediated collagen binding in arthritogenicity of Yersinia enterocolitica serotype O:8: experimental studies with rats.
- Construction and characterization of an isogenic urease-negative mutant of Helicobacter mustelae.
- Urease-negative Nocardia asteroides causing cutaneous nocardiosis.
