Correlation of virus polypeptide structure with attenuation of poliovirus type 1.

AUTOR(ES)
RESUMO

Several avirulent samples of poliovirus type 1 derived in the process attenuating the neurovirulent Mahoney strain show an altered virus capsid polypeptide, VP-1, on polyacrylamide gel electrophoresis of sodium dodecyl sulfate-disrupted virions.

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