Criteria for categorizing early biochemical events occurring during sporulation of Bacillus subtilis.
AUTOR(ES)
Dancer, B N
RESUMO
Two criteria are suggested for assessing the relevance of biochemical events occurring early in sporulation. The first is thymidine starvation, a condition known to inhibit sporulation. This also inhibits the production of metalloprotease, serine protease, and ribonuclease; alpha-amylase production, however, is unaffected. The second is the effect of a regulator mutation which increases the production of the proteases. In the mutant, ribonuclease is produced in correspondingly large quantities whereas alpha-amylase production is unaffected. We conclude that, whereas the serine protease is part of the main sequence of events leading to formation of the spore, the metalloprotease is a side effect, i.e., connected with the main sequence but not part of it. Ribonuclease could, on present evidence, be either in the main sequence or a side effect associated with it. Amylase, however, seems to be separately regulated and neither directly nor indirectly connected with the sporulation sequence.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=245945Documentos Relacionados
- Characterization of cell cycle events during the onset of sporulation in Bacillus subtilis.
- Requirement for peptidoglycan synthesis during sporulation of Bacillus subtilis.
- Cloning of an early sporulation gene in Bacillus subtilis.
- Expression of a Bacillus megaterium sporulation-specific gene during sporulation of Bacillus subtilis.
- INTRACELLULAR EVENTS OCCURRING DURING ENDOTROPHIC SPORULATION IN BACILLUS MYCOIDES1