Crystalline arrays of membrane-bound acetylcholine receptor.
AUTOR(ES)
Kistler, J
RESUMO
Electron micrographs of tubular structures with a crystalline arrangement of membrane-bound acetylcholine receptor oligomers have been analyzed by digital image reconstruction. The receptor molecules are oriented synaptic side out, and in projection they appear to be asymmetric and have a defined orientation. All four subunits are contained in the oligomers as demonstrated by immunoelectron microscopy; these structures therefore appear to be suitable for subunit localization in the oligomer.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=319634Documentos Relacionados
- Structural details of membrane-bound acetylcholine receptor from Tropedo marmorata.
- Dimeric arrangement and structure of the membrane-bound acetylcholine receptor studied by electron microscopy.
- Reconstitution of functional membrane-bound acetylcholine receptor from isolated Torpedo californica receptor protein and electroplax lipids.
- Volatile anesthetic facilitation of in vitro desensitization of membrane-bound acetylcholine receptor from Torpedo californica
- In vitro selection of RNA molecules that displace cocaine from the membrane-bound nicotinic acetylcholine receptor