Cutaneous graft-versus-host disease after hematopoietic stem cell transplant - a review

AUTOR(ES)

Villarreal, Cesar Daniel Villarreal, Alanis, Julio Cesar Salas, Pérez, Jose Carlos Jaime, Candiani, Jorge Ocampo

FONTE

An. Bras. Dermatol.

DATA DE PUBLICAÇÃO

2016-06

RESUMO

Abstract Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplants (allo-HSCT) associated with significant morbidity and mortality. The earliest and most common manifestation is cutaneous graft-versus-host disease. This review focuses on the pathophysiology, clinical features, prevention and treatment of cutaneous graft-versus-host disease. We discuss various insights into the disease's mechanisms and the different treatments for acute and chronic skin graft-versus-host disease.

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