Cyclic AMP receptor protein from yeast mitochondria: submitochondrial localization and preliminary characterization.
AUTOR(ES)
Rödel, G
RESUMO
We have identified and characterized a cyclic AMP receptor protein in mitochondria of the yeast Saccharomyces cerevisiae. The binding is specific for cyclic nucleotides, particularly for cyclic AMP which is bound with high affinity (Kd of 10(-9) M) at 1 to 5 pmol/mg of mitochondrial protein. The mitochondrial cyclic AMP receptor is synthesized on cytoplasmic ribosomes and has an apparent molecular weight of 45,000 as determined by photoaffinity labeling. It is localized in the inner mitochondrial membrane and faces the intermembrane space. Cross-contamination of mitochondrial inner membranes by plasma membranes or soluble cytoplasmic proteins is excluded.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=214827Documentos Relacionados
- Phospholipid Metabolism in Plant Mitochondria: Submitochondrial Sites of Synthesis 1
- A receptor molecule for estrogens: isolation from the rat uterus and preliminary characterization.
- Phospholipid Metabolism in Plant Mitochondria: II. SUBMITOCHONDRIAL SITES OF SYNTHESIS OF PHOSPHATIDYLCHOLINE AND PHOSPHATIDYLETHANOLAMINE 1
- Cyclic AMP binding proteins and cyclic AMP-dependent protein kinase from Blastocladiella emersonii.
- Positive regulation of the colicin E1 gene by cyclic AMP and cyclic AMP receptor protein.