Cytological Evidence for Association of the Ends of the Linear Chromosome in Streptomyces coelicolor

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

The chromosome of the filamentous bacterium Streptomyces coelicolor is linear, but the genetic map is circular. We present cytological evidence based on the use of fluorescence in situ hybridization showing that the ends of the chromosome frequently colocalize, in agreement with the idea that the ends are held together, effectively forming a circular chromosome. These observations provide a possible explanation for how a linear bacterial chromosome can exhibit a circular genetic map.

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