Decreased elastin in vessel walls puts the pressure on

AUTOR(ES)

D’Armiento, Jeanine

FONTE

American Society for Clinical Investigation

RESUMO

Mice haploinsufficient for elastin develop structural changes in vessel walls similar to those seen in patients with mutations in the elastin gene. A new study demonstrates that due to mechanical changes in the vessel wall, these animals exhibit increased mean arterial pressures. The results evoke the possibility that alterations in elastin may contribute to the development of essential hypertension in patients.

Documentos Relacionados

• Crystals and vessel walls
• Mapping strain exerted on blood vessel walls using deuterium double-quantum-filtered MRI
• The source of NMR-detected motional anisotropy of water in blood vessel walls.
• Effect of albumin on the osmotic pressure exerted by myoglobin across capillary walls in frog mesentery.
• Inconclusive evidence puts Adderall back on the market