Defective parvoviruses acquired via the transplacental route protect mice against lethal adenovirus infection.
AUTOR(ES)
Lipps, B V
RESUMO
Adeno-associated virus type 1 (AAV-1) interfered with the replication of its murine adenovirus (MAV) helper in primary mouse kidney cells and in 1-day-old ICR mice. Mice carrying AAV-1 acquired via the transplacental route were protected against lethal infection with MAV. The replication of AAV-1 in these mice could be triggered by multiple challenges with MAV, and antibodies to AAV-1 were subsequently detected.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=347512Documentos Relacionados
- Raccoon poxvirus recombinants expressing the rabies virus nucleoprotein protect mice against lethal rabies virus infection.
- Replication-defective mutants of herpes simplex virus (HSV) induce cellular immunity and protect against lethal HSV infection.
- Partially purified antigen preparations of Toxoplasma gondii protect against lethal infection in mice.
- What immunity can protect against HIV infection.
- Vaccinated Mice Remain More Susceptible to Mycobacterium tuberculosis Infection Initiated via the Respiratory Route than via the Intravenous Route
