DEVELOPMENT OF ORAL NIFEDIPINE-LOADED POLYMERIC NANOCAPSULES: PHYSICOCHEMICAL CHARACTERISATION, PHOTOSTABILITY STUDIES, IN VITRO AND IN VIVO EVALUATION
AUTOR(ES)
Tagliari, Monika Piazzon, Granada, Andrea, Silva, Marcos Antonio Segatto, Stulzer, Hellen Karine, Zanetti-Ramos, Betina Giehl, Fernandes, Daniel, Silva, Izabella Thais, Simões, Claudia Maria Oliveira, Sordi, Regina, Assreuy, Jamil, Soldi, Valdir
FONTE
Quím. Nova
DATA DE PUBLICAÇÃO
2015-07
RESUMO
In this study, nifedipine (NFP)-loaded polymeric nanocapsules were prepared and characterised with a view to protect the drug from degradation. Nanocapsule suspensions were prepared using two different surfactants (pluronic F68 and polyvinyl alcohol). Physicochemical stability and
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