Developmental origin and early differentiation of retinal Müller cells in mice.
AUTOR(ES)
Bhattacharjee, J
RESUMO
During the prenatal development of the retina in mice Müller cells at the initial stage of differentiation show a high level of histochemically detectable non-specific esterase activity. These are the first of the retinal cell types to differentiate and appear at the 11th day of gestation along the vitreal border in the central retina. As development proceeds they appear in more peripheral areas and their perikarya migrate outwardly and become scattered throughout the depth of the retina. Appearance of presumptive Müller cells is followed by rapid growth of the retina and differentiation of the inner retinal layers. With the progress of histogenesis from the central to the peripheral areas the esterase activity in the Müller cells gradually diminishes. The possible significance of early differentiation of Müller cells in promoting growth and histogenesis of retina is discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1231976Documentos Relacionados
- Oestrogen and the differentiation of granulated metrial gland cells in chimeric mice.
- Identification and developmental expression of a smooth-muscle gamma-actin in postmeiotic male germ cells of mice.
- Ionic and electrophysiological properties of retinal Müller (glial) cells of the turtle.
- Early Differentiation of Glucagon-Producing Cells in Embryonic Pancreas: A Possible Developmental Role for Glucagon*
- Thrombin-induced inhibition of potassium currents in human retinal glial (Müller) cells.