Directional asymmetries in the length-response profiles of cells in the feline dorsal lateral geniculate nucleus.

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1. The visual cortex provides a major synaptic input to the dorsal lateral geniculate nucleus (dLGN). Cortical layer VI cells giving rise to this projection are strongly influenced by stimulus orientation, length and direction of motion. In the dLGN, a significant component of the strong length tuning exhibited by most cells follows from the corticofugal influence. We have now checked whether there are directional biases in geniculate cell responses, and whether such biases are influenced by stimulus length. 2. The responses of A-laminae dLGN cells were assessed by single-unit extracellular recording. Length preference was examined by plotting multihistogram length-tuning curves to moving bars of light of various length. 3. Over half of the cells tested (100/183) exhibited directional bias and in many cases, this bias was highly dependent on bar length, resulting in radically different length response profiles for the two directions of motion. These asymmetries are similar to those documented for cortical hypercomplex cells, but do not equate to any known facet of the centre-surround organization of dLGN cell receptive fields. 4. We suspected the directional biases followed from the influence of the corticofugal projection. To test this, we recorded from preparations where areas 17 and 18 of the visual cortex had been removed. Surprisingly, a similar proportion of cells exhibited directional biases after removal of the corticofugal input, suggesting that the biases are generated subcortically. 5. The widespread presence of systematic biases in the response profiles of dLGN cells further underlines the possibility that geniculate mechanisms may make a far greater contribution to visual processing than hitherto suspected.

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