Disk diffusion susceptibility testing of ticarcillin plus clavulanic acid.
AUTOR(ES)
Fuchs, P C
RESUMO
Disk diffusion susceptibility testing of ticarcillin plus the beta-lactamase inhibitor clavulanic acid was performed on 489 clinical isolates, and the results were compared with reference broth microdilution susceptibilities. Four different disks containing 75 micrograms of ticarcillin plus 2.5, 5, 10, and 15 micrograms of clavulanic acid were evaluated. Based on test performance and clavulanic acid stability, the 75-10-micrograms disk is recommended. Interpretive criteria for ticarcillin as published by the National Committee for Clinical Laboratory Standards appear to be satisfactory for the combination drug, but because the number of ticarcillin-clavulanic acid-resistant isolates was small, this proposal must be considered only tentative.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=271119Documentos Relacionados
- Discrepancies between disk diffusion and broth susceptibility studies of the activity of ticarcillin plus clavulanic acid against ticarcillin-resistant Pseudomonas aeruginosa.
- Reassessment of susceptibility test interpretive criteria for ticarcillin and ticarcillin-clavulanic acid.
- Ticarcillin and Ticarcillin-Clavulanic Acid Susceptibility Tests: Error Rates for Disk Tests with Consecutively Isolated Members of the Family Enterobacteriaceae
- Ticarcillin and ticarcillin-clavulanic acid susceptibility tests: error rates for disk tests with consecutively isolated members of the family Enterobacteriaceae.
- Ex vivo pharmacodynamic study of piperacillin alone and in combination with tazobactam, compared with ticarcillin plus clavulanic acid.
