Dissociation of Vesicular Stomatitis Virus and Relation of the Virion Proteins to the Viral Transcriptase
AUTOR(ES)
Bishop, D. H. L.
RESUMO
A procedure has been developed for the sequential removal and purification of the glycoprotein and membrane protein of vesicular stomatitis virus (VSV). Neither of these proteins exhibited transcriptase activity. All of the activity was recovered in the ribonucleic acid (RNA)-ribonucleoprotein complex of VSV, which also has four other minor proteins associated with it. During transcription of 41% of the RNA of a virus preparation, no dissociation of the ribonucleoprotein from the viral RNA was observed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=356455Documentos Relacionados
- Initiation and Direction of RNA Transcription by Vesicular Stomatitis Virus Virion Transcriptase
- Rebinding of transcriptase components (L and NS proteins) to the nucleocapsid template of vesicular stomatitis virus.
- Assembly of viral membranes: nature of the association of vesicular stomatitis virus proteins to membranes.
- Dissociation and Reconstitution of the Transcriptase and Template Activities of Vesicular Stomatitis B and T Virions
- Comparison of Vesicular Stomatitis Virus Intracellular and Virion Ribonucleoproteins
