Effect of Acyclovir on Latent Herpes Simplex Virus Infections in Trigeminal Ganglia of Mice†
AUTOR(ES)
Klein, Richard J.
RESUMO
The inhibition by acyclovir of the in vitro reactivation of herpes simplex virus from latently infected ganglion explant cultures is dependent on the continuous presence of this drug. Administration of acyclovir subcutaneously, orally, or by continuous perfusion to mice with established latent infections did not eliminate latent virus from the trigeminal ganglia.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=181548Documentos Relacionados
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