Effect of anti-mu-chain-specific immunosuppression on Chikungunya virus encephalitis of mice.
AUTOR(ES)
Giovarelli, M
RESUMO
Mice neonatally immunosuppressed with anti-mu antiserum failed to produce circulating antibodies to sheep erythrocytes and showed a marked decrease in circulating immunoglobulins. However, when they were intracerebrally infected with Chikungunya virus (a group A togavirus), they showed a mortality rate consistently lower than non-immunosuppressed control mice. Several possible explanations for this finding are discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=421040Documentos Relacionados
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