Effect of Gentamicin on Growth of Viral, Chlamydial, and Rickettsial Agents in Mice and Embryonated Eggs

AUTOR(ES)

White, Lendell A.

RESUMO

Gentamicin, at concentrations up to 500 μg/ml, showed no effect on the replication, yield, or infectivity of seven viruses or on the agents of psittacosis and meningopneumonitis when grown in mice or embryonated eggs. At the 500 μg/ml level, lymphogranuloma venereum cultures had a slight reduction in infectivity. Rickettsia akari demonstrated susceptibility at the 5 μg/ml level, whereas R. rickettsii, R. mooseri, and R. canada grown in embryonated eggs were susceptible in varying degrees to gentamicin at or above the 50 μg/ml concentration.

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