Effect of Glucagon on Net Splanchnic Cyclic AMP Production in Normal and Diabetic Men
AUTOR(ES)
Liljenquist, John E.
RESUMO
Glucagon activates hepatic adenylate cyclase, thereby increasing acutely the liver content of cyclic AMP (cAMP) as well as the release of cAMP into the hepatic vein. Insulin, on the other hand, antagonizes this glucagon-mediated cAMP production, thus providing a hypothetical mechanism through which insulin might correct some of the metabolic abnormalities of diabetes.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=301454Documentos Relacionados
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