Effect of Plantago australis leaves on different gastric ulcer models
AUTOR(ES)
Bürger, M.E., Ghedini, P.C., Baldisserotto, B., Palmeiro, N.M.S., Almeida, C.E., Lenzi, C.F., Silva, A.C., Oliveira, C.Q.
FONTE
Revista Brasileira de Farmacognosia
DATA DE PUBLICAÇÃO
2002
RESUMO
The anti-ulcerogenic effect of the crude ethanolic extract (CEE) of Plantago australis leaves was tested against ethanol-, indomethacin-, and cold restrain-induced stress ulcers. The CEE (500 and 1000 mg/kg) reduced the lesion index (LI) and the ulcer index in ethanol-induced ulcers, and the dose of 1000 mg/kg increased the amount of mucous. The highest dose of the CEE reduced the LI of cold restraint-induced stress ulcers when compared to the control group. The indomethacin-induced ulcers were not affected by this extract.
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