Effect of Some Inhibitors Derived from Nitrite on Macromolecular Synthesis in Bacillus cereus
AUTOR(ES)
Hansen, J. N.
RESUMO
The effect of several inhibitors derived from nitrite on incorporation of [14C]uracil into ribonucleic acid of Bacillus cereus during outgrowth and vegetative growth has been determined. A heat-induced inhibitor presumably of the Perigo type was compared with the nitrosothiols of thioglycolate and β-mercaptoethanol. All were found to effectively inhibit uracil incorporation at all stages tested. Phase-contrast microscopy revealed that inhibition of morphological events occurred either before germination or during early outgrowth, depending on inhibitor concentration. It was also found that a precursor to the heat-induced inhibitor could be isolated from dialyzable tryptone (a pancreatic digest of casein), which chromatographed as a single species on diethylaminoethyl-cellulose and Sephadex G-25, with an apparent molecular weight of about 2,000.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=187285Documentos Relacionados
- Macromolecular Synthesis During Microcycle Sporogenesis of Bacillus cereus T
- Effect of Putative Deoxyribonucleic Acid Inhibitors on Macromolecular Synthesis in Saccharomyces cerevisiae
- EFFECT OF ENZYME INHIBITORS ON THE GERMINATION AND RESPIRATION OF AND GROWTH FROM BACILLUS CEREUS VAR. TERMINALIS SPORES1
- Effect of Trimethoprim on Macromolecular Synthesis in Escherichia coli
- Effect of inhibitors of trypsin-like proteolytic enzymes Bacillus cereus T spore germination.
