Effects of a new cardioselective beta-adrenergic blocker (tolamolol) on exercise tolerance in patients with angina pectoris

AUTOR(ES)

Sood, N. K.

RESUMO

The effect of oral and intravenous tolamolol on exercise tolerance was assessed in 11 patients with angina pectoris. Patients were selected on the basis of an absence of placebo response and the reliable reproducibility of anginal pain and electrocardiographic changes with exercise on a constant load Schönander-Elema bicycle ergometer. The effect of tolamolol on exercise time and heart rate was compared with that of propranolol. Tolamolol was shown to increase exercise tolerance and the effect was comparable to that of propranolol. Tolamolol did not produce a significant increase in airways resistance nor were any untoward side effects noted.

Documentos Relacionados

• Effects of the cardioselective beta-adrenergic receptor blocking agent metoprolol in angina pectoris. Subacute study with exercise tests.
• Effect of a new beta-adrenergic blocking agent, ICI 66o82, on exercise haemodynamics and airway resistance in angina pectoris.
• Beta-Adrenergic Receptor Blockers and Nitrates for Angina Pectoris
• Ocular hypotensive effect of atenolol (Tenormin, I.C.I.). A new beta-adrenergic blocker.
• Pharmacodynamic Effects of Beta-Adrenergic Receptor Blockade in Patients with Hyperthyroidism *