Effects of a small serosal hydrostatic pressure on sodium and water transport and morphology in rabbit gall-bladder

AUTOR(ES)
RESUMO

1. In order to investigate the mechanism of serosal pressure-induced inhibition of isosmotic fluid transport, the effect of 4·5 cm water serosal pressure on spontaneous water transfer (Jv) in rabbit gall-bladders was measured (in the presence of a supporting soft nylon net on the mucosal side) in a modified Ussing chamber. This allowed unidirectional Na+ fluxes ([Formula: see text] and [Formula: see text]), transepithelial potential difference and resistance (Rt) to be measured simultaneously. The effects of the serosal pressure were also investigated by light and electron microscopy.

Documentos Relacionados