Effects of burn injury in mucous and stomach myenteric plexus structure of rats. / Efeitos da lesão térmica corporal na mucosa e nos componentes do plexo mioentérico do estômago de ratos.
AUTOR(ES)
Paulo Alexandre Galvanini
DATA DE PUBLICAÇÃO
2008
RESUMO
The enteric nervous system is located among the layer constituents of the gastrintestinal tract. Between the longitudinal and circular muscle layers, which extend throughout the digestory tract from the esophagus to the rectum. Gastrintestinal disorders are common complications caused by burn injury. This research evaluates, in stomach of rats changes in the mucosal and myenteric plexus, subjected burn injury. The number of neurons NADH-d and NADPH-d significantly increased in burned animals. Analyzing the average area of the profile of the neurons NADH-dr and NADPH-dr, showed a significant decrease of 26% and 24%, respectively, in the area of the profile of the neurons of the burned animals. Thus, the association of VIP, NO and acetylcholine is presented so as to interfere with gastric emptying causing changes in the mucosal wich were observed by the technique of MEV. With this data, it can be conclude that the burn injury interferes in the myenteric plexus of the stomach of rats causing a gastroparesis.
ASSUNTO(S)
burning sistema nervoso entérico gastric mucosa queimadura enteric nervous system stomach estômago plexo mioentérico myenteric plexus mucosa gástrica
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