Effects of hypoxia on catecholamine synthesis in rabbit carotid body in vitro

AUTOR(ES)

Fidone, S.

RESUMO

1. Unanaesthetized, unrestrained rabbits were exposed for 3 hr in a chamber to either air, hypoxic gas mixtures (10% or 14% O2 in N2) or a hyperoxic gas mixture (50% O2 in N2). The carotid bodies were then removed and incubated for 3 hr in modified Tyrode media equilibrated with 100% O2 and containing either [3H]tyrosine or [3H]DOPA. The contents of [3H]DA and [3H]NA in the tissue were determined as described in the preceding paper.

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