Efficacies of Clarithromycin Regimens against Mycobacterium xenopi in Mice
AUTOR(ES)
Lounis, Nacer
FONTE
American Society for Microbiology
RESUMO
Mice were infected intravenously with 3.5 × 107 CFU of Mycobacterium xenopi and treated with various clarithromycin-containing regimens or left untreated for 4 weeks. All nine of the clarithromycin-containing regimens reduced the CFU counts to the levels below the pretreatment values, indicating that these regimens had a bactericidal effect on M. xenopi in mice. The rifampin-isoniazid-ethambutol regimen was significantly less bactericidal than clarithromycin alone or clarithromycin-containing combined regimens.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=90813Documentos Relacionados
- Efficacies of liposome-encapsulated clarithromycin and ofloxacin against Mycobacterium avium-M. intracellulare complex in human macrophages.
- Activity of clarithromycin against Mycobacterium avium complex infection in beige mice.
- Effectiveness of Once-Weekly Rifapentine and Moxifloxacin Regimens against Mycobacterium tuberculosis in Mice
- Comparative activities of azithromycin and clarithromycin against Mycobacterium avium infection in beige mice.
- Efficacies of selected disinfectants against Mycobacterium tuberculosis.