Efficacy of Sulforaphane in Eradicating Helicobacter pylori in Human Gastric Xenografts Implanted in Nude Mice
AUTOR(ES)
Haristoy, Xavier
FONTE
American Society for Microbiology
RESUMO
Sulforaphane, an isothiocyanate abundant in the form of its glucosinolate precursor in broccoli sprouts, has shown in vitro activity against Helicobacter pylori. We evaluated the effect of sulforaphane in vivo against this bacterium by using human gastric xenografts in nude mice. H. pylori was completely eradicated in 8 of the 11 sulforaphane-treated grafts. This result suggests that sulforaphane might be beneficial in the treatment of H. pylori-infected individuals.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=296232Documentos Relacionados
- Human Embryonic Gastric Xenografts in Nude Mice: a New Model of Helicobacter pylori Infection
- Inhibitory effect of Dendrobium officinale polysaccharide on human gastric cancer cell xenografts in nude mice
- Infectious cycle of human papillomavirus type 11 in human foreskin xenografts in nude mice.
- Does eradicating H pylori improve gastric symptoms?
- Detection of Helicobacter pylori gene expression in human gastric mucosa.
