Electrophoretic Variation for X Chromosome-Linked Hypoxanthine Phosphoribosyl Transferase (Hprt) in Wild-Derived Mice
AUTOR(ES)
Chapman, Verne M.
RESUMO
An electrophoretic variation for hypoxanthine phosphoribosyltransferase, HPRT, has been identified in samples of Mus spretus, a field mouse from southern Europe and in M. m. castaneus, a house mouse from southeast Asia. These mice will interbreed with laboratory mice to produce viable, fertile F1 progeny. The variation for HPRT segregates as an X chromosome gene in F1 and backcross progeny. Linkage analysis involving the markers Pgk-1 and Ags indicated a gene order of centromere— Hprt—Pgk-1—Ags in crosses involving both stocks of wild mice.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1202054Documentos Relacionados
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