Enhancement of the transforming capacity of BK virus by partial deletion of the 68-base-pair tandem repeats.

AUTOR(ES)
RESUMO

We constructed a set of deleted BK viral DNAs that lack part of the triplicated 68-base-pair (bp) sequences (the central unit has an 18-bp deletion) and assayed them for capacity to transform hamster kidney cells. Deletion of one of the two 68-bp units remarkably enhanced transforming capacity.

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