ENZYME SYSTEMS IN THE MYCOBACTERIA XV. : Initial Steps in the Metabolism of Glycerol1

AUTOR(ES)

Goldman, Dexter S.

RESUMO

Goldman, Dexter S. (Veterans Administration Hospital, Madison, Wis.). Enzyme systems in the mycobacteria. XV. Initial steps in the metabolism of glycerol. J. Bacteriol. 86:30–37. 1963.—In cell-free extracts of strain H37Ra of Mycobacterium tuberculosis, glycerol is metabolized first by oxidation to dihydroxyacetone. A kinase was partially purified and shown to phosphorylate dihydroxyacetone; in the presence of the glyceraldehyde-3-phosphate dehydrogenase system, the product of the kinase reaction was further oxidized to 3-phosphoglycerate. The role of α-glycerol phosphate in the metabolism of strain H37Ra is discussed.

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