Epidemiology of Group B Streptococcal Disease in the United States: Shifting Paradigms
AUTOR(ES)
Schuchat, Anne
FONTE
American Society for Microbiology
RESUMO
Since its emergence 25 years ago, group B streptococcus has become recognized as a cause of serious illness in newborns, pregnant women, and adults with chronic medical conditions. Heavy colonization of the genital tract with group B streptococcus also increases the risk that a woman will deliver a preterm low-birthweight infant. Early-onset infections (occurring at <7 days of age) are associated with much lower fatality than when they were first described, and their incidence is finally decreasing as the use of preventive antibiotics during childbirth increases among women at risk. New serotypes of group B streptococcus have emerged as important pathogens in adults and newborns. Clinical and laboratory practices—in obstetrics, pediatrics, and clinical microbiology—have an impact on disease and/or its prevention, and protocols established at the institutional level appear to be critical tools for the reduction of perinatal disease due to group B streptococcus. Since intrapartum antibiotics will prevent at best only a portion of the full burden of group B streptococcal disease, critical developments in vaccine evaluation, including study of polysaccharide-protein conjugate vaccines, offer the potential for enhanced prevention in the relatively near future.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=88893Documentos Relacionados
- Susceptibility of the Bacteroides fragilis group in the United States: analysis by site of isolation.
- HEALTH PROGRESS IN THE UNITED STATES: 1900-1960
- Hospital libraries in the United States: historical antecedents.
- Serologic Testing for Celiac Disease in the United States: Results of a Multilaboratory Comparison Study
- Hospital librarianship in the United States: at the crossroads
