Establishment of a murine cell line resistant to arabinosyladenine and devoid of adenosine deaminase activity.

AUTOR(ES)
RESUMO

A population of cells stably resistant to a concentration of arabinosyladenine 100-fold greater than that tolerated by wild-type cells was selected over a period of 15 months. The cells are not cross resistant to arabinosylcytosine and may have at least one kinase with altered substrate specificity.

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