Evidence for a Set of Closely Linked Autosomal Genes That Interact with Sex-Chromosome Heterochromatin in DROSOPHILA MELANOGASTER
AUTOR(ES)
Sandler, L.
RESUMO
It is proposed that there exists a special region in the euchromatin of the left arm of chromosome 2 (contained within sections 31–32 of the standard salivary gland chromosome map) that is defined by a set of genes, each one of which interacts with a specific sex-chromosome heterochromatic segment. The evidence for the existence of this region is, first, the exhibition, mapping, and analysis of five different maternal-effect, embryonic semi-lethals located in region 31–32. Secondly, in each case the consequence of the maternal effect is markedly influenced by the amount of X- or Y-chromosome heterochromatin carried by the progeny of mutant mothers. The nature of this interaction and possible reasons for the existence of the cluster of autosomal genes are discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1213695Documentos Relacionados
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