EVIDENCE FOR ONE FUNCTIONAL PHENYLALANYL TRNA BINDING SITE ON THE 30S RIBOSOMAL SUBUNIT*

AUTOR(ES)

Igarashi, Kazuei

RESUMO

NH2 terminal analysis of polyphenylalanine formed from 30S subunit-bound 14C-phenylalanyl-tRNA suggests that there is only one site in a 30S subunit for specific binding of phenylalanyl-tRNA. Assuming that no movement of the bound phenylalanyl-tRNA takes place during association of 30S subunits with 50S ribosomal subunits, the binding site of the 30S ribosomal subunit corresponds to site 2 (—NH2 side with respect to the growing polypeptide chain) of the two binding sites of 70S ribosomes.

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