Evidence suggesting that virulence maps to the P1 region of the coxsackievirus B4 genome.
AUTOR(ES)
Ramsingh, A
RESUMO
A chimeric virus containing the P1 region of a virulent variant of coxsackievirus B4 and the P2 and P3 regions of a nonvirulent strain was constructed from cDNA clones. The chimeric virus induced pancreatitis with concurrent hypoglycemia similar to that observed in mice infected with the virulent variant.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=249496Documentos Relacionados
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