Extensive Immunoglobulin Binding of Plasmodium falciparum-Infected Erythrocytes in a Group of Children with Moderate Anemia
AUTOR(ES)
Scholander, Carin
FONTE
American Society for Microbiology
RESUMO
Immunoglobulins (Ig) from healthy, nonimmune individuals bind to the surfaces of Plasmodium falciparum-infected erythrocytes (RBC). In order to investigate the presence of this parasite phenotype in wild isolates and its potential association with malarial anemia, we conducted a study of 207 anemic or nonanemic children with malaria in Gabon. Surface Ig binding to infected RBC was detected for 83% of the isolates. No difference in Ig binding between the groups was observed, but all isolates which exhibited extensive Ig binding were found in a group of moderately anemic children.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=107901Documentos Relacionados
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