Extração de bifenilas policloradas de amostras de leite materno: otimização univariada versus planejamento experimental
AUTOR(ES)
Kowalski, Cláudia Hoffmann, Augusto, Fabio, Godoy, Helena Teixeira
FONTE
Quím. Nova
DATA DE PUBLICAÇÃO
2013
RESUMO
The convenience of the multivariate optimization of SPME procedures through ANOVA calculated using Doehlert designs has been demonstrated for twelve PCBs in the complex matrix of milk. For this study, the main parameters of the extraction were selected and valued through univariate and multivariate optimization. In addition, the analysis of variance allowed identification of the statistically significant variables in this model: high temperature (95 ºC) and ionic strength (36% m/v) proved significant for all the PCBs while intermediate time (70 min) and low methanol concentration (5% v/v) also contributed to the extraction of the majority of these PCBs.
Documentos Relacionados
- O legado das bifenilas policloradas (PCBs)
- Planejamento experimental na otimização da extração dos frutos de Syzygium cumini (L.) skeels
- Polychlorinated biphenyls in the Brazilian breast milk : development of analytical methodology and evaluation of the contamination
- Catalytic hydrodechlorination of polychlorinated biphenyls (PCBs)
- Estudo do coeficiente de partição octanol-água de bifenilas policloradas (PCBs) utilizando parâmetros topológicos