Formation of dTDP-Rhamnose Is Essential for Growth of Mycobacteria
AUTOR(ES)
Ma, Yufang
FONTE
American Society for Microbiology
RESUMO
It was determined that the dTDP-rhamnose synthesis gene, rmlD, could be inactivated in Mycobacterium smegmatis only in the presence of a rescue plasmid carrying functional rmlD. Hence, dTDP-rhamnose biosynthesis is essential for the growth of mycobacteria and the targeting of dTDP-rhamnose synthesis for new tuberculosis drugs is supported.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=135104Documentos Relacionados
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