FRD3, a Member of the Multidrug and Toxin Efflux Family, Controls Iron Deficiency Responses in Arabidopsis

AUTOR(ES)

Rogers, Elizabeth E.

FONTE

American Society of Plant Biologists

RESUMO

We present the cloning and characterization of an Arabidopsis gene, FRD3, involved in iron homeostasis. Plants carrying any of the three alleles of frd3 constitutively express three strategy I iron deficiency responses and misexpress a number of iron deficiency–regulated genes. Mutant plants also accumulate approximately twofold excess iron, fourfold excess manganese, and twofold excess zinc in their shoots. frd3-3 was first identified as man1. The FRD3 gene is expressed at detectable levels in roots but not in shoots and is predicted to encode a membrane protein belonging to the multidrug and toxin efflux family. Other members of this family have been implicated in a variety of processes and are likely to transport small organic molecules. The phenotypes of frd3 mutant plants, which are consistent with a defect in either iron deficiency signaling or iron distribution, indicate that FRD3 is an important component of iron homeostasis in Arabidopsis.

Documentos Relacionados

• FRD3 Controls Iron Localization in Arabidopsis1
• Arabidopsis ALF5, a Multidrug Efflux Transporter Gene Family Member, Confers Resistance to Toxins
• AtOPT3, a Member of the Oligopeptide Transporter Family, Is Essential for Embryo Development in Arabidopsis
• res2+, a new member of the cdc10+/SWI4 family, controls the 'start' of mitotic and meiotic cycles in fission yeast.
• Arabidopsis AtGPAT1, a Member of the Membrane-Bound Glycerol-3-Phosphate Acyltransferase Gene Family, Is Essential for Tapetum Differentiation and Male Fertility