Function and Immunochemistry of Prekallikrein-High Molecular Weight Kininogen Complex in Plasma
AUTOR(ES)
Scott, Cheryl F.
RESUMO
Plasma from individuals with high molecular weight (HMW) kininogen deficiency has been reported to be deficient in prekallikrein as measured by radial immunodiffusion, prekallikrein coagulant activity, and/or kaolin-activated arginine esterase activity. The discovery that prekallikrein and HMW kininogen circulate as a complex in plasma led us to reevaluate the antigenic and functional properties of prekallikrein in HMW kininogen-deficient plasma as well as in normal plasma.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=371379Documentos Relacionados
- Identification of prekallikrein and high-molecular-weight kininogen as a complex in human plasma.
- Interactions among Hageman factor, plasma prekallikrein, high molecular weight kininogen, and plasma thromboplastin antecedent.
- Prekallikrein deficiency in a kindred with kininogen deficiency and Fitzgerald trait clotting defect. Evidence that high molecular weight kininogen and prekallikrein exist as a complex in normal human plasma.
- Activation and function of human Hageman factor. The role of high molecular weight kininogen and prekallikrein.
- Hageman factor, high molecular weight kininogen, and prekallikrein in chronic liver disease.