Functional obstruction: the renal pelvis rules

AUTOR(ES)
FONTE

American Society for Clinical Investigation

RESUMO

Failure in the peristaltic mechanism that conducts urine from the kidney to the bladder can lead to hydronephrosis, a common birth defect associated with obstructive nephropathy. New animal models reveal molecular pathways important for peristalsis and point to the central role of the renal pelvis in urine transport.

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